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57% of Healthy Adults Already Have Plaque
Silent Atherosclerosis: 57% of Healthy Adults Already Have PlaqueA new study just imaged the arteries of 16,808 adults who had no known heart disease. No prior heart attack. No stroke. No stents. No...
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VESALIUS-CV: Repatha Cut All-Cause Mortality by 20% in Primary Prevention
Repatha Cut All-Cause Death by 20% in People Who Never Had a Heart AttackMost large cholesterol trials are built to show fewer heart attacks and strokes. Very few of them are built to show fewer deaths...
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Colchicine With No Cardiovascular Benefits
Colchicine and Heart Disease: Reading the Negative Trials HonestlyI want to walk you through one of the more interesting stories in cardiology right now, because it is not a story about a drug that...
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Frank's Sign: What a Crease in the Earlobe Can Tell You About Your Heart
Frank's Sign: Does It Mean You Have Heart DiseaseIn 1973, an American pulmonologist named Sanders T. Frank published a brief report noting something peculiar about his patients with coronary artery...
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Your Brain Doesn't Need Cholesterol
Statins, Cholesterol, And Your BrainYour brain does not need circulating cholesterol. In fact, cholesterol circulating in your blood stream inside of lipoproteins can not get into your brain. Lipid...
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Lipid And Cholesterol Metabolism In Depth Review
Intestinal Absorption of CholesterolHaving an overall understanding of lipid and lipoprotein metabolism is important to understanding how we arrive at cholesterol in our arteries and develop...
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Finland Goes From Highest Cardiovascular Mortality To Lowest
North Karelia Finland 84% Reduction In Death RatesIn a beautiful example of how dietary and lifestyle interventions work, the country of Finland was able to reduce cardiovascular mortality by 84% in...
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Your Morning Coffee and Your Heart: What the American Heart Association...
Your Morning Coffee and Your Heart: What the American Heart Association Actually FoundCaffeine is the most widely consumed drug on the planet, and most people drinking it have no idea what it does to...
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Statins In Primary And Secondary Prevention! What the Latest Data Shows!
Four Types of Prevention and the Power of Lowering LDLThe old model of preventing heart disease had two categories. Modern cardiology has four, and knowing where you fall could change the course of...
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A Pill That Cuts LDL by 57 Percent: The Oral PCSK9 Inhibitor That Changes...
New Oral PCSK9 Breakthrough EnlicitideA new oral PCSK9 inhibitor called enlicitide decanoate just produced results in a major randomized trial that rival injectable therapies, and the cardiovascular...
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Best Congestive Heart Failure Treatment: What the Evidence Shows
Best Congestive Heart Failure Treatment: What the Evidence ShowsCongestive heart failure used to have an 80% five-year mortality rate. This means that in 5 years, 80% of those diagnosed with CHF would...
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A Weight Loss Drug Just Cut Heart Attacks and Strokes by 20 Percent. And You...
Ozempic Cuts Heart Attacks and Strokes by 20 Percent In Non DiabeticsI have been a huge proponent of GLP1 medications since they first hit the market in 2005. I also run a cardiometabolic, obesity, and...
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Why Most Heart Attacks Happen With Normal LDL Levels: Understanding the Real...
Why Most Heart Attacks Happen With Normal Cholesterol?Every single day on social media, I get the same question: "Dr. Alo, if most people having heart attacks have normal cholesterol, then isn't...
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What If You Have Pre Everything? Should You Wait?
The Metabolic "Grey Zone" in Young Adults: Why You Shouldn't WaitWhat if you have "Pre Everything"? Pre-diabetes, pre-hypertension, pre-dyslipidemia. What's your risk? Should you wait until it gets...
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History Of Cholesterol: Over 250 Years Of Chemistry
The History of Cholesterol: From Mummies and Gallstones to ApoB and Gene EditingI have spent my career explaining cholesterol to patients, and one thing I have learned is that the whole subject makes...
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1 Million People Say Low LDL Means You Live Longer!
Is Low LDL Cholesterol Dangerous? What a Million-Person Genetic Study Reveals About Cholesterol and LifespanOne of the most persistent myths I hear in my cardiology practice goes something like this:...
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Why Desis Get Heart Disease? Earlier And More Severe
Why Do Desis Get So Much Heart Disease? A Cardiologist Explains.Why people from India and Pakistan develop heart disease earlier, more often, and more severely than almost any other ethnic population...
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What Is apoB? Cardiologist Explains!
What Is ApoB? A Cardiologist Explains Apolipoprotein B, the Best Predictor of Heart Attack RiskLet me tell you the number I care about more than almost anything else on your lipid panel. It is not your...
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Do Statins Reduce All Cause Mortality? New Research Says Yes!
Do Statins Help You Live Longer? What the Mortality Data Actually ShowsThere is a version of the statin debate that lives entirely online, where the drugs are framed as a way to lower a number on a lab...
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When To Start Treating Cholesterol? The Sooner The More Benefit You Get!
The Cholesterol Paradox: Why Lower-Risk Patients Get the Biggest Benefit From TreatmentFor years the standard advice has gone something like this: wait until your risk is high enough, then we will...
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